The Nigrostriatal Pathway in Creutzfeldt-Jakob Disease
نویسندگان
چکیده
منابع مشابه
The nigrostriatal pathway in Creutzfeldt-Jakob disease.
Parkinsonism, chorea, and dystonia are well-known clinical manifestations of Creutzfeldt-Jakob disease (CJD), but lesions of the nigrostriatal pathway have never been thoroughly studied. We performed a detailed neuropathologic study of the nigrostriatal pathway in 15 sporadic CJD and 2 variant CJD cases that included clinical correlations and assessment of neuron subtype loss, distribution of p...
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Background: Creutzfeldt-Jakob disease (CJD) as a life-threatening neurodegenerative disorder is not usually diagnosed in early stages of the disease because of a variety in its clinical manifestations. This study aimed to present a middle-aged woman with psychiatric symptoms who ultimately was diagnosed as a CJD case. Case presentation: This 48-year-old woman had progressive symptoms of depres...
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The ‘‘pulvinar sign’’ on MRI brain scan is defined as hyperintensity of the posterior thalamus relative to the signal intensity of the anterior putamen. In the appropriate clinical context, the pulvinar sign and hyperintensity in the dorsomedial thalamic nuclei (the hockey stick sign) are sensitive and specific features of variant Creutzfeldt– Jakob disease (vCJD). Variant CJD is an acquired fo...
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BACKGROUND The determination of the form of prion disease and early diagnosis are important for prognostic, public health, and epidemiologic reasons. OBJECTIVE To describe a patient with sporadic Creutzfeldt-Jakob disease (sCJD) who had a clinical history and initial electroencephalogram and magnetic resonance imaging findings consistent with variant CJD (vCJD). RESULTS Results of a repeate...
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The following is an overview of the emerging issue of handling the dead human body with Creutzfeldt-Jakob Disease. The purpose is to educate the reader to what the disease is and is not and to better prepare the funeral service professional cremationist to service clientele while protecting the public end employees of the crematory. Creutzfeldt-Jakob Disease (CJD) is a relatively new disease ha...
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ژورنال
عنوان ژورنال: Journal of Neuropathology & Experimental Neurology
سال: 2009
ISSN: 0022-3069,1554-6578
DOI: 10.1097/nen.0b013e3181abdae8